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Chromatin and gene regulation [[electronic resource] ] : mechanisms in epigenetics / / Bryan M. Turner
| Chromatin and gene regulation [[electronic resource] ] : mechanisms in epigenetics / / Bryan M. Turner |
| Autore | Turner Bryan M |
| Pubbl/distr/stampa | Oxford ; ; Malden, MA, : Blackwell Science, 2001 |
| Descrizione fisica | 1 online resource (298 p.) |
| Disciplina | 572.865 |
| Soggetto topico |
Chromatin
Genetic regulation |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-281-32244-X
9786611322441 0-470-75062-6 0-470-75167-3 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Chromatin and Gene Regulation; Contents; Preface; Prologue; Chapter 1 Controlling Transcription: Shared Aims and Common Mechanisms; Introduction; Some general principles; Transcription in prokaryotes; Genetic switches in bacteria; Chapter 2 Transcription in Eukaryotes: The Problems of Complexity; Introduction; The emergence of eukaryotes; The transcription machinery in eukaryotes; General transcription factors, TAFs and the PolII pre-initiation complex; Transcription by PolI and PolIII; The elongation stage; Experimental considerations; Large genome problems: why are things so complicated?
Chapter 3 The Nucleosome: Chromatin's Structural UnitIntroduction; Exploring how DNA is packaged in the nucleus; The structure of the nucleosome; Chapter 4 Histone Tails: Modifications and Epigenetic Information; Introduction; The histone tails; Histone modifications; Histone variants; Chapter 5 Higher-Order Chromatin Structures and Nuclear Organization; Introduction; The 30 nm fibre; DNA loops; The nuclear matrix and chromosome scaffolds; Scaffold/matrix associated regions (SARs and MARs); Chromosome bands and functional domains; Nuclear domains and structure in the interphase nucleus Chapter 6 Transcription in a Chromatin EnvironmentIntroduction; Genes are packaged into nucleosomes, even when they are being transcribed; Genetic experiments in yeast show the importance of histones for gene regulation; Changes in chromatin structure precede gene activation; Increased histone acetylation can precede or accompany the onset of transcription; DNaseI hypersensitive sites; Nucleosome positioning in vitro and in vivo; Chromatin domains; Chapter 7 How the Transcription Machinery Deals with Chromatin; Introduction; In vitro studies of transcription factor binding A crowded nucleosome: Mouse Mammary Tumour Virus nucleosome BThe opportunities presented by DNA replication; Chromatin and the elongation stage of transcription; Chapter 8 Chromatin Remodelling Machines; Introduction; Nucleosome remodelling enzymes; Histone acetyltransferases (HATs); Histone deacetylases; The nuclear receptors; Chromatin and cancer; Chapter 9 Heterochromatin; Introduction; α and β heterochromatin in Drosophila; Facultative and constitutive heterochromatin; Heterochromatin DNA; Heterochromatin genes; Heterochromatin proteins; Position effect variegation Heterochromatin and gene expression in mammalsChapter 10 Long-term Silencing of Gene Expression; Introduction; DNA methylation; Silencing at telomeres and mating type loci in yeast; Chapter 11 Cellular Memory and Imprinting; Introduction; Maintenance of transcriptional states; Imprinted genes; Chapter 12 Mechanisms of Dosage Compensation; Introduction; Methods of sex determination; Dosage compensation in mammals; Dosage compensation in Drosophila; Dosage compensation in C. elegans; Lessons from dosage compensation; Index |
| Record Nr. | UNINA-9910145414903321 |
Turner Bryan M
|
||
| Oxford ; ; Malden, MA, : Blackwell Science, 2001 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Chromatin and gene regulation [[electronic resource] ] : mechanisms in epigenetics / / Bryan M. Turner
| Chromatin and gene regulation [[electronic resource] ] : mechanisms in epigenetics / / Bryan M. Turner |
| Autore | Turner Bryan M |
| Pubbl/distr/stampa | Oxford ; ; Malden, MA, : Blackwell Science, 2001 |
| Descrizione fisica | 1 online resource (298 p.) |
| Disciplina | 572.865 |
| Soggetto topico |
Chromatin
Genetic regulation |
| ISBN |
1-281-32244-X
9786611322441 0-470-75062-6 0-470-75167-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Chromatin and Gene Regulation; Contents; Preface; Prologue; Chapter 1 Controlling Transcription: Shared Aims and Common Mechanisms; Introduction; Some general principles; Transcription in prokaryotes; Genetic switches in bacteria; Chapter 2 Transcription in Eukaryotes: The Problems of Complexity; Introduction; The emergence of eukaryotes; The transcription machinery in eukaryotes; General transcription factors, TAFs and the PolII pre-initiation complex; Transcription by PolI and PolIII; The elongation stage; Experimental considerations; Large genome problems: why are things so complicated?
Chapter 3 The Nucleosome: Chromatin's Structural UnitIntroduction; Exploring how DNA is packaged in the nucleus; The structure of the nucleosome; Chapter 4 Histone Tails: Modifications and Epigenetic Information; Introduction; The histone tails; Histone modifications; Histone variants; Chapter 5 Higher-Order Chromatin Structures and Nuclear Organization; Introduction; The 30 nm fibre; DNA loops; The nuclear matrix and chromosome scaffolds; Scaffold/matrix associated regions (SARs and MARs); Chromosome bands and functional domains; Nuclear domains and structure in the interphase nucleus Chapter 6 Transcription in a Chromatin EnvironmentIntroduction; Genes are packaged into nucleosomes, even when they are being transcribed; Genetic experiments in yeast show the importance of histones for gene regulation; Changes in chromatin structure precede gene activation; Increased histone acetylation can precede or accompany the onset of transcription; DNaseI hypersensitive sites; Nucleosome positioning in vitro and in vivo; Chromatin domains; Chapter 7 How the Transcription Machinery Deals with Chromatin; Introduction; In vitro studies of transcription factor binding A crowded nucleosome: Mouse Mammary Tumour Virus nucleosome BThe opportunities presented by DNA replication; Chromatin and the elongation stage of transcription; Chapter 8 Chromatin Remodelling Machines; Introduction; Nucleosome remodelling enzymes; Histone acetyltransferases (HATs); Histone deacetylases; The nuclear receptors; Chromatin and cancer; Chapter 9 Heterochromatin; Introduction; α and β heterochromatin in Drosophila; Facultative and constitutive heterochromatin; Heterochromatin DNA; Heterochromatin genes; Heterochromatin proteins; Position effect variegation Heterochromatin and gene expression in mammalsChapter 10 Long-term Silencing of Gene Expression; Introduction; DNA methylation; Silencing at telomeres and mating type loci in yeast; Chapter 11 Cellular Memory and Imprinting; Introduction; Maintenance of transcriptional states; Imprinted genes; Chapter 12 Mechanisms of Dosage Compensation; Introduction; Methods of sex determination; Dosage compensation in mammals; Dosage compensation in Drosophila; Dosage compensation in C. elegans; Lessons from dosage compensation; Index |
| Record Nr. | UNISA-996203975303316 |
|
Turner Bryan M
|
||
| Oxford ; ; Malden, MA, : Blackwell Science, 2001 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Chromatin and gene regulation [[electronic resource] ] : mechanisms in epigenetics / / Bryan M. Turner
| Chromatin and gene regulation [[electronic resource] ] : mechanisms in epigenetics / / Bryan M. Turner |
| Autore | Turner Bryan M |
| Pubbl/distr/stampa | Oxford ; ; Malden, MA, : Blackwell Science, 2001 |
| Descrizione fisica | 1 online resource (298 p.) |
| Disciplina | 572.865 |
| Soggetto topico |
Chromatin
Genetic regulation |
| ISBN |
1-281-32244-X
9786611322441 0-470-75062-6 0-470-75167-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Chromatin and Gene Regulation; Contents; Preface; Prologue; Chapter 1 Controlling Transcription: Shared Aims and Common Mechanisms; Introduction; Some general principles; Transcription in prokaryotes; Genetic switches in bacteria; Chapter 2 Transcription in Eukaryotes: The Problems of Complexity; Introduction; The emergence of eukaryotes; The transcription machinery in eukaryotes; General transcription factors, TAFs and the PolII pre-initiation complex; Transcription by PolI and PolIII; The elongation stage; Experimental considerations; Large genome problems: why are things so complicated?
Chapter 3 The Nucleosome: Chromatin's Structural UnitIntroduction; Exploring how DNA is packaged in the nucleus; The structure of the nucleosome; Chapter 4 Histone Tails: Modifications and Epigenetic Information; Introduction; The histone tails; Histone modifications; Histone variants; Chapter 5 Higher-Order Chromatin Structures and Nuclear Organization; Introduction; The 30 nm fibre; DNA loops; The nuclear matrix and chromosome scaffolds; Scaffold/matrix associated regions (SARs and MARs); Chromosome bands and functional domains; Nuclear domains and structure in the interphase nucleus Chapter 6 Transcription in a Chromatin EnvironmentIntroduction; Genes are packaged into nucleosomes, even when they are being transcribed; Genetic experiments in yeast show the importance of histones for gene regulation; Changes in chromatin structure precede gene activation; Increased histone acetylation can precede or accompany the onset of transcription; DNaseI hypersensitive sites; Nucleosome positioning in vitro and in vivo; Chromatin domains; Chapter 7 How the Transcription Machinery Deals with Chromatin; Introduction; In vitro studies of transcription factor binding A crowded nucleosome: Mouse Mammary Tumour Virus nucleosome BThe opportunities presented by DNA replication; Chromatin and the elongation stage of transcription; Chapter 8 Chromatin Remodelling Machines; Introduction; Nucleosome remodelling enzymes; Histone acetyltransferases (HATs); Histone deacetylases; The nuclear receptors; Chromatin and cancer; Chapter 9 Heterochromatin; Introduction; α and β heterochromatin in Drosophila; Facultative and constitutive heterochromatin; Heterochromatin DNA; Heterochromatin genes; Heterochromatin proteins; Position effect variegation Heterochromatin and gene expression in mammalsChapter 10 Long-term Silencing of Gene Expression; Introduction; DNA methylation; Silencing at telomeres and mating type loci in yeast; Chapter 11 Cellular Memory and Imprinting; Introduction; Maintenance of transcriptional states; Imprinted genes; Chapter 12 Mechanisms of Dosage Compensation; Introduction; Methods of sex determination; Dosage compensation in mammals; Dosage compensation in Drosophila; Dosage compensation in C. elegans; Lessons from dosage compensation; Index |
| Record Nr. | UNINA-9910830814203321 |
|
Turner Bryan M
|
||
| Oxford ; ; Malden, MA, : Blackwell Science, 2001 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Chromatin and gene regulation [[electronic resource] ] : mechanisms in epigenetics / / Bryan M. Turner
| Chromatin and gene regulation [[electronic resource] ] : mechanisms in epigenetics / / Bryan M. Turner |
| Autore | Turner Bryan M |
| Pubbl/distr/stampa | Oxford ; ; Malden, MA, : Blackwell Science, 2001 |
| Descrizione fisica | 1 online resource (298 p.) |
| Disciplina | 572.865 |
| Soggetto topico |
Chromatin
Genetic regulation |
| ISBN |
1-281-32244-X
9786611322441 0-470-75062-6 0-470-75167-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Chromatin and Gene Regulation; Contents; Preface; Prologue; Chapter 1 Controlling Transcription: Shared Aims and Common Mechanisms; Introduction; Some general principles; Transcription in prokaryotes; Genetic switches in bacteria; Chapter 2 Transcription in Eukaryotes: The Problems of Complexity; Introduction; The emergence of eukaryotes; The transcription machinery in eukaryotes; General transcription factors, TAFs and the PolII pre-initiation complex; Transcription by PolI and PolIII; The elongation stage; Experimental considerations; Large genome problems: why are things so complicated?
Chapter 3 The Nucleosome: Chromatin's Structural UnitIntroduction; Exploring how DNA is packaged in the nucleus; The structure of the nucleosome; Chapter 4 Histone Tails: Modifications and Epigenetic Information; Introduction; The histone tails; Histone modifications; Histone variants; Chapter 5 Higher-Order Chromatin Structures and Nuclear Organization; Introduction; The 30 nm fibre; DNA loops; The nuclear matrix and chromosome scaffolds; Scaffold/matrix associated regions (SARs and MARs); Chromosome bands and functional domains; Nuclear domains and structure in the interphase nucleus Chapter 6 Transcription in a Chromatin EnvironmentIntroduction; Genes are packaged into nucleosomes, even when they are being transcribed; Genetic experiments in yeast show the importance of histones for gene regulation; Changes in chromatin structure precede gene activation; Increased histone acetylation can precede or accompany the onset of transcription; DNaseI hypersensitive sites; Nucleosome positioning in vitro and in vivo; Chromatin domains; Chapter 7 How the Transcription Machinery Deals with Chromatin; Introduction; In vitro studies of transcription factor binding A crowded nucleosome: Mouse Mammary Tumour Virus nucleosome BThe opportunities presented by DNA replication; Chromatin and the elongation stage of transcription; Chapter 8 Chromatin Remodelling Machines; Introduction; Nucleosome remodelling enzymes; Histone acetyltransferases (HATs); Histone deacetylases; The nuclear receptors; Chromatin and cancer; Chapter 9 Heterochromatin; Introduction; α and β heterochromatin in Drosophila; Facultative and constitutive heterochromatin; Heterochromatin DNA; Heterochromatin genes; Heterochromatin proteins; Position effect variegation Heterochromatin and gene expression in mammalsChapter 10 Long-term Silencing of Gene Expression; Introduction; DNA methylation; Silencing at telomeres and mating type loci in yeast; Chapter 11 Cellular Memory and Imprinting; Introduction; Maintenance of transcriptional states; Imprinted genes; Chapter 12 Mechanisms of Dosage Compensation; Introduction; Methods of sex determination; Dosage compensation in mammals; Dosage compensation in Drosophila; Dosage compensation in C. elegans; Lessons from dosage compensation; Index |
| Record Nr. | UNINA-9910841330803321 |
|
Turner Bryan M
|
||
| Oxford ; ; Malden, MA, : Blackwell Science, 2001 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||